The Helix and the Hard Road celebrates the work of Joan Slonczewski and Jo Walton, WisCon 37's Guests of Honor. The volume includes Slonczewski's essay "I Have No Time, and I Must Write" and her short fiction "Tuberculosis Bacteria Joins the UN," and a previously unpublished collection of Walton's poetry, "The River and the Road." In addition, the authors talk at length with interviewers knowledgeable about their work: Walton with Lynne M. Thomas, and Slonczewski with Michael Levy.