"The supernatural detective team known as Mystery Inc. is back for a new round of eerie adventures! Canine mystery-solver Scooby-Doo and his team of fellow sleuths, Shaggy, Velma, Daphne, and Fred, head to Midvale, home of Supergirl. She enlists the gang's help when she's haunted by the ghosts of her home planet, Krypton. Can they discover the secret behind these alien specters? Then, they meet up with super-dog Dynomutt, who's worried about his partner, Blue Falcon. Falcon appears to be possessed, and it's up to the gang to save him! Mystery Inc. has even more crazy capers in store. They travel back in time to take on historical menaces from World War II with the legendary JSA! And as soon as they're back to reality, they enter the spooky bayou home of Swamp Thing, who needs help stopping the villainous Voodoo Queen. What secrets of the swamp does the Queen guard? Next, the gang takes on a group of notorious gangsters known as the Ant Hill Mob, followed by a team of simian super-villains, including Gorilla Grodd, Monsieur Mallah, and the Ultra-Humanite. Then it's time for Mystery Inc.'s craziest adventure yet, alongside the misfit superhero group known as the Doom Patrol! The World's Strangest Heroes--Elasti-Girl, Negative Man, and Robotman, led by the Chief--enlist the help of Mystery Inc. as they take on some seriously weird evildoers.