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The Gene: An Intimate History par Siddhartha…
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The Gene: An Intimate History (original 2016; édition 2016)

par Siddhartha Mukherjee (Auteur)

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1,732597,381 (4.18)113
The Pulitzer Prize-winning author draws on his scientific knowledge and research to describe the magisterial history of a scientific idea, the quest to decipher the master-code of instructions that makes and defines humans; that governs our form, function, and fate; and that determines the future of our children. The story of the gene begins in earnest in an obscure Augustinian abbey in Moravia in 1856 where Gregor Mendel, a monk working with pea plants, stumbles on the idea of a "unit of heredity." It intersects with Darwin's theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms postwar biology. It invades discourses concerning race and identity and provides startling answers to some of the most potent questions coursing through our political and cultural realms. It reorganizes our understanding of sexuality, gender identity, sexual orientation, temperament, choice, and free will, thus raising the most urgent questions affecting our personal realms. Above all, the story of the gene is driven by human ingenuity and obsessive minds--from Mendel and Darwin to Francis Crick, James Watson, and Rosalind Franklin to the thousands of scientists working today to understand the code of codes. Woven through the book is the story of Mukherjee's own family and its recurring pattern of schizophrenia, a haunting reminder that the science of genetics is not confined to the laboratory but is vitally relevant to everyday lives. The moral complexity of genetics reverberates even more urgently today as we learn to "read" and "write" the human genome--unleashing the potential to change the fates and identities of our children and our children's children.--Adapted from dust jacket.… (plus d'informations)
Membre:octal
Titre:The Gene: An Intimate History
Auteurs:Siddhartha Mukherjee (Auteur)
Info:Scribner (2016), Edition: Illustrated, 608 pages
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The Gene: An Intimate History par Siddhartha Mukherjee (2016)

  1. 00
    p53: The Gene that Cracked the Cancer Code par Sue Armstrong (rodneyvc)
  2. 00
    A Brief History of Everyone Who Ever Lived: The Human Story Retold Through Our Genes par Adam Rutherford (jigarpatel)
    jigarpatel: Summary of how humans have evolved with evidence found in genetics; interesting follow-up to Gene: An Intimate History.
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» Voir aussi les 113 mentions

Si vous souhaitez mettre à jour vos connaissances sur la génétique, précipitez vous sur la traduction du dernier livre de l'oncologue Siddhartha Mukherjee - prix Pulitzer pour son précédent essai sur le cancer. Cette histoire de la génétique met en perspective, d'une manière très mesurée et pédagogique, l'histoire de la recherche génétique..En 600 pages vous allez pouvoir refaire le point sur le grand débat entre l'inné et l'acquis, remettre en perspective les annonces sensationnelles de 100 ans de progrès médicaux. Ce page-turner a la très grande qualité de ne jamais simplifier les choses tout en les rendant extrêmement claires. Très accessible, il permet de remettre en contexte cet avenir qui s'annonce, de saisir que l'héritable n'est pas le transmissible, que l'édition génomique n'est pas si simple, et que les barrières morales de la médecine, toujours mouvantes et poreuses, ne sont pas inexistantes. Heureusement ! ( )
  hubertguillaud | Sep 23, 2017 |
The story of this invention and this discovery has been told, piecemeal, in different ways, but never before with the scope and grandeur that Siddhartha Mukherjee brings to his new history, “The Gene.” ... As he did in his Pulitzer ­Prize-winning history of cancer, “The Emperor of All Maladies” (2010), Mukherjee views his subject panoptically, from a great and clarifying height, yet also intimately.
 
... By the time “The Gene” is over, Dr. Mukherjee has covered Mendel and his peas, Darwin and his finches. He’s taken us on the quest of Watson, Crick and their many unsung compatriots to determine the stuff and structure of DNA. We learn about how genes were sequenced, cloned and variously altered, and about the race to map our complete set of DNA, or genome, which turns out to contain a stunning amount of filler material with no determined function.

...Many of the same qualities that made “The Emperor of All Maladies” so pleasurable are in full bloom in “The Gene.” The book is compassionate, tautly synthesized, packed with unfamiliar details about familiar people....

... “The Gene” is more pedagogical than dramatic; as often as not, the stars of this story are molecules, not humans. Dr. Mukherjee still has a poignant personal connection to the material — mental illness has wrapped itself around his family tree like a stubborn vine, claiming two uncles and a cousin on his father’s side — but this book does not aim for the gut. It aims for the mind...
 

» Ajouter d'autres auteur(e)s (4 possibles)

Nom de l'auteur(e)RôleType d'auteurŒuvre ?Statut
Siddhartha Mukherjeeauteur(e) principal(e)toutes les éditionscalculé
Boutsikaris, DennisNarrateurauteur secondairequelques éditionsconfirmé
Drost-Plegt, TraceyTraducteurauteur secondairequelques éditionsconfirmé
Veen, René vanTraducteurauteur secondairequelques éditionsconfirmé
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An exact determination of the laws of heredity will probably work more change in man's outlook on the world, and in his power over nature, than any other advance in natural knowledge that can be foreseen.
—William Bateson
Human beings are ultimately nothing but carriers—passageways—for genes.  They ride us into the ground like racehorses from generation to generation.  Genes don't think about what constitutes good or evil.  They don't care whether we are happy or unhappy.  We're just means to an end for them.  The only thing they think about is what is most efficient for them.
—Haruki Murakami, IQ84
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To Priyabala Mukherjee (1906-1985), who knew the perils;
to Carrie Buck (1906-1983), who experienced them.
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In the winter of 2012, I traveled from Delhi to Calcutta to visit my cousin Moni.
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The Pulitzer Prize-winning author draws on his scientific knowledge and research to describe the magisterial history of a scientific idea, the quest to decipher the master-code of instructions that makes and defines humans; that governs our form, function, and fate; and that determines the future of our children. The story of the gene begins in earnest in an obscure Augustinian abbey in Moravia in 1856 where Gregor Mendel, a monk working with pea plants, stumbles on the idea of a "unit of heredity." It intersects with Darwin's theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms postwar biology. It invades discourses concerning race and identity and provides startling answers to some of the most potent questions coursing through our political and cultural realms. It reorganizes our understanding of sexuality, gender identity, sexual orientation, temperament, choice, and free will, thus raising the most urgent questions affecting our personal realms. Above all, the story of the gene is driven by human ingenuity and obsessive minds--from Mendel and Darwin to Francis Crick, James Watson, and Rosalind Franklin to the thousands of scientists working today to understand the code of codes. Woven through the book is the story of Mukherjee's own family and its recurring pattern of schizophrenia, a haunting reminder that the science of genetics is not confined to the laboratory but is vitally relevant to everyday lives. The moral complexity of genetics reverberates even more urgently today as we learn to "read" and "write" the human genome--unleashing the potential to change the fates and identities of our children and our children's children.--Adapted from dust jacket.

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